FIG. 6.
Demyelination in the spinal cord white matter of transgenic mice following TMEV infection. VP1+ (A), LP+ (B), RP+ (C), VP1− (D), LP− (E), and RP− (F) mice were infected with TMEV for 45 days, and spinal cord blocks were then embedded in glycol-methacrylate plastic. Sections were stained with erichrome-cresyl violet stain to detect demyelination and inflammation. Focal areas of demyelination are shown for LP1+ (A) and LP+ (B) transgenic mice. No demyelination was observed for RP+ (C), VP1− (D), LP− (E), or RP− (F) mice.