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Cross-reactivity of the OA-antiserum with other biogenic amines was determined with enzyme-linked immunosobent assay (ELISA). The percent inhibition (ordinate) of binding of OA-antibody is shown in relation to the concentration (abscissa) of the tested amines. The test shows no or low cross-reaction with serotonin, DOPA and dopamine. In contrast, the activity of the MAb-OA1 is inhibited by epinephrine and less so by tyramine and norepinephrine.
