Table 1.

Resubstitution analysis of TFAM performance with the MSDB

Model	Na	Snb	Spc	Seq1d	Seq2e
Af	52	100	91	A: 33 [48,5]	V: −3 [21,−26]
A w/o acg	52	98	91	A: 29 [44,3]	V: −1 [22,−24]
C	13	100	92	C: 24 [37,0]	S: −12 [5,−34]
C w/o ac	13	100	92	C: 21 [33,−3]	S: −12 [8,−35]
D	21	100	100	D: 20 [37,4]	E: −3 [7,−11]
D w/o ac	21	100	100	D: 17 [34,1]	E: −4 [6,−12]
E	23	100	100	E: 38 [54,15]	D: −11 [3,−37]
E w/o ac	23	100	100	E: 34 [51,11]	D: −11 [3,−37]
F	22	100	100	F: 23 [30,11]	C: −16 [−1,−33]
F w/o ac	22	100	100	F: 19 [26,7]	K: −11 [−1,−23]
G	45	100	100	G: 26 [46,6]	W: −14 [−2,−30]
G w/o ac	45	100	100	G: 22 [42,2]	H: −11 [0,−19]
H	15	100	100	H: 23 [36,12]	Q: −14 [−7,−22]
H w/o ac	15	100	100	H: 19 [32,8]	Q: −15 [−8,−23]
I	61	96	95	I: 27 [38,−25]	K: −10 [0,−35]
I w/o ac	61	95	95	I: 24 [35,−27]	R: −6 [8,−37]
K	22	100	95	K: 16 [28,7]	N: −10 [−1,−22]
K w/o ac	22	100	95	K: 13 [25,4]	F: −7 [0,−20]
L	63	100	100	L: 61 [79,30]	Y: −13 [4,−54]
L w/o ac	63	100	100	L: 59 [77,28]	Y: −10 [7,−51]
M	14	92	100	M: 13 [18,−7]	X: −10 [−4,−14]
M w/o ac	14	78	100	M: 10 [15,−10]	X: −13 [−7,−17]
N	21	100	100	N: 20 [32,1]	K: −12 [−4,−23]
N w/o ac	21	95	95	N: 16 [29,−2]	K: −12 [−5,−23]
P	28	100	100	P: 29 [36,6]	X: −12 [−4,−23]
P w/o ac	28	100	100	P: 25 [34,4]	X: −7 [0,−17]
Q	19	100	100	Q: 30 [39,0]	H: −16 [−5,−33]
Q w/o ac	19	100	100	Q: 27 [36,−2]	C: −15 [−6,−29]
R	48	100	100	R: 20 [32,5]	N: −8 [−2,−29]
R w/o ac	48	100	96	R: 18 [25,3]	N: −4 [1,−25]
S	53	100	100	S: 77 [104,44]	Y: 0 [18,−23]
S w/o ac	53	100	100	S: 74 [101,44]	Y: 0 [19,−22]
T	43	100	100	T: 17 [24,6]	N: −8 [4,−14]
T w/o ac	43	100	93	T: 14 [21,4]	N: −7 [5,−13]
V	26	73	100	V: 14 [25,0]	A: 4 [14,−13]
V w/o ac	26	69	94	V: 11 [22,−1]	A: 4 [14,−13]
W	18	100	100	W: 23 [30,1]	G: −17 [−2,−33]
W w/o ac	18	94	100	W: 20 [26,−2]	G: −17 [−1,−30]
Xh	28	100	100	X: 46 [51,29]	M:−28 [−8,−48]
X w/o ac	28	100	100	X: 42 [47,25]	P:−23 [−9,−54]
Y	20	100	100	Y: 45 [64,31]	S:7 [33,−11]
Y w/o ac	20	100	100	Y: 41 [60,28]	S:9 [35,−8]
Average	655	98.1	98.7
Average w/o ac	655	96.6	97.7

^aTraining set size.

^bModel percent sensitivity.

^cModel percent specificity.

^dSequence class with highest median score against the model and its distribution: median and range.

^eSequence class with second-highest median score against the model and its distribution: median and range.

^fSequences are scored against the model including the anticodon positions.

^gw/o ac = without anticodon. Sequences are scored against the model excluding the anticodon positions.

^htRNA^iMet.