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. 2026 Oct 5;16(46):60280–60291. doi: 10.1039/d6ra07298d

Table 2. Summary of Michaelis–Menten and Lineweaver–Burk plot results from enzyme kinetics assays of 1f.

Compound Inhibition constant, Ki (µM) Alpha (α) Goodness of fit (R2) Mechanism of inhibition
1f 85.9 3.5 0.98 Mixed-type inhibition (competitive preference)