Table 2. Summary of Michaelis–Menten and Lineweaver–Burk plot results from enzyme kinetics assays of 1f.
| Compound | Inhibition constant, Ki (µM) | Alpha (α) | Goodness of fit (R2) | Mechanism of inhibition |
|---|---|---|---|---|
| 1f | 85.9 | 3.5 | 0.98 | Mixed-type inhibition (competitive preference) |