FIG. 3.
The tvbr allele contains a premature stop codon. A schematic drawing of TVB is shown depicting the signal peptide (SP), cysteine-rich domains (CRDs), membrane spanning domain (MSD), and cytoplasmic death domain. The nucleotide and amino acid sequences are also shown surrounding the single nucleotide change that distinguishes tvbr from tvbs1 (numbered from the start methionine codon). The premature stop codon in tvbr is indicated by an asterisk and a BfaI site unique to tvbr is shown in a box.