Table 2.

Univariate analysis of body composition predictors of mortality in RVD subjects.

Predictors of mortality	HR	CI 95%	p value
Men	1.40	0.82 to 2.39	0.207
Age, years	1.04	1.02 to 1.07	<0.001
Comorbidities
Hypertension	1.21	0.72 to 2.03	0.463
COPD	0.87	0.51 to 1.49	0.627
CKD	1.14	0.51 to 2.54	0.743
Diabetes	0.68	0.38 to 1.22	0.203
Asthma	1.37	0.43 to 4.41	0.588
Heart failure	1.73	0.97 to 3.08	0.062
Heart failure type
HFrEF	1.65	0.74 to 3.66	0.216
HFmrEF	0.91	0.26 to 3.12	0.887
HFpEF	1.97	1.06 to 3.65	0.030
Body composition parameters
Weight, kg	0.98	0.96 to 0.99	0.004
Height, cm	1.00	0.97 to 1.02	0.798
BMI	0.93	0.90 to 0.97	0.001
Obesity	0.43	0.25 to 0.73	0.002
Handgrip strength, kg	0.96	0.93 to 0.99	0.015
Phase angle < 5 °	2.85	1.63 to 4.97	<0.001
TBW, %	1.03	0.99 to 1.06	0.064
ECW, %	1.01	0.97 to 1.05	0.502
ICW, %	1.04	0.96 to 1.12	0.283
Impedance index >0.84	1.86	1.00 to 3.48	0.050
Fat mass, %	0.96	0.93 to 0.98	0.002
ASMMI	0.73	0.58 to 0.91	0.006
6MWD, meters	0.99	0.99 to 0.99	<0.001
Low performance	2.95	1.44 to 6.00	0.003
Body composition phenotypes
Preserved strength and muscle mass, n (%)	1	Reference
Dynapenia, n (%)	2.41	1.08 to 5.37	0.031
Muscle wasting, n (%)	1.73	0.53 to 5.64	0.359
Sarcopenia, n (%)	4.66	2.13 to 10.19	<0.001
Cachexia, n (%)	6.09	2.16 to 17.15	0.001

COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; HFrEF, heart failure with reduced ejection fraction; HFmrEF, heart failure with mildly reduced ejection fraction; HFpEF, heart failure with preserved ejection fraction; BMI, body mass index; TBW, total body water; ECW, extracellular water; ICW, intracellular water; ASMMI, appendicular skeletal muscle mass index; 6MWD, 6-min walk distance.