Table 1.
Participant characteristics by fourths of total mean accelerometer-measured physical activity volume levels.
| Characteristics | Overall | Q1 | Q2 | Q3 | Q4 |
|---|---|---|---|---|---|
| n | 95,197 | 23,824 | 23,821 | 23,772 | 23,780 |
| Sex | |||||
| Female | 53,632 (56.3) | 11,896 (49.9) | 13,550 (56.9) | 14,049 (59.1) | 14,137 (59.4) |
| Male | 41,565 (43.7) | 11,928 (50.1) | 10,271 (43.1) | 9,723 (40.9) | 9,643 (40.6) |
| Age at accelerometer assessment | 62.31 (7.85) | 65.07 (7.31) | 63.08 (7.63) | 61.58 (7.73) | 59.50 (7.65) |
| BMI (kg/m2) | 26.71 (4.53) | 28.45 (5.15) | 26.96 (4.40) | 26.25 (4.09) | 25.17 (3.70) |
| Townsend Index scorea | −1.73 (2.82) | −1.59 (2.90) | −1.78 (2.80) | −1.81 (2.77) | −1.74 (2.80) |
| College degree or equivalent | 42,471 (44.6) | 9,820 (41.2) | 10,782 (45.3) | 10,856 (45.7) | 11,013 (46.3) |
| Cigarette smoking | |||||
| Never | 54,326 (57.1) | 12,613 (52.9) | 13,565 (56.9) | 13,908 (58.5) | 14,240 (59.9) |
| Previous | 34,248 (36.0) | 9,071 (38.1) | 8,649 (36.3) | 8,387 (35.3) | 8,141 (34.2) |
| Current | 6,623 (7.0) | 2,140 (9.0) | 1,607 (6.7) | 1,477 (6.2) | 1,399 (5.9) |
| Alcohol consumption | |||||
| Never | 5,381 (5.7) | 1,657 (7.0) | 1,277 (5.4) | 1,215 (5.1) | 1,232 (5.2) |
| <1 time/week | 19,350 (20.3) | 5,660 (23.8) | 4,744 (19.9) | 4,595 (19.3) | 4,351 (18.3) |
| 1–2 time/week | 23,887 (25.1) | 5,751 (24.1) | 6,028 (25.3) | 5,997 (25.2) | 6,111 (25.7) |
| 3–4 time/week | 24,809 (26.1) | 5,469 (23.0) | 6,153 (25.8) | 6,465 (27.2) | 6,722 (28.3) |
| >4 time/week | 21,770 (22.9) | 5,287 (22.2) | 5,619 (23.6) | 5,500 (23.1) | 5,364 (22.6) |
| Pre-existing chronic conditions | |||||
| Cardiovascular disease | 5,498 (5.8) | 2,451 (10.3) | 1,402 (5.9) | 1,034 (4.3) | 611 (2.6) |
| Hypertension | 25,782 (27.1) | 9,415 (39.5) | 6,832 (28.7) | 5,488 (23.1) | 4,047 (17.0) |
| Diabetes | 4,408 (4.6) | 2,216 (9.3) | 1,030 (4.3) | 721 (3.0) | 441 (1.9) |
| Regular use of NSAIDsb | 23,785 (25.0) | 6,987 (29.3) | 6,035 (25.3) | 5,614 (23.6) | 5,149 (21.7) |
| Antibiotic use in past 3 months | 1,289 (1.4) | 310 (1.3) | 313 (1.3) | 335 (1.4) | 331 (1.4) |
| Female-specific variables | |||||
| Postmenopause | 36,279 (67.6) | 8,552 (71.9) | 9,446 (69.7) | 9,422 (67.1) | 8,859 (62.7) |
| Parity | |||||
| 0 | 11,504 (21.4) | 2,509 (21.1) | 2,850 (21.0) | 2,988 (21.3) | 3,157 (22.3) |
| 1–2 | 30,601 (57.1) | 6,765 (56.9) | 7,765 (57.3) | 8,033 (57.2) | 8,038 (56.9) |
| 3+ | 11,527 (21.5) | 2,622 (22.0) | 2,935 (21.7) | 3,028 (21.6) | 2,942 (20.8) |
| Ever use of oral contraceptives | 45,778 (85.4) | 9,767 (82.1) | 11,553 (85.3) | 12,131 (86.3) | 12,327 (87.2) |
| Ever use of HRT | 20,852 (38.9) | 5,639 (47.4) | 5,684 (41.9) | 5,216 (37.1) | 4,313 (30.5) |
| LPA (min/week) | 2121.9 (690.2) | 1526.9 (464.3) | 2005.8 (478.1) | 2296.8 (549.9) | 2659.6 (687.0) |
| MVPA (min/week) | 290.1 (243.3) | 145.5 (127.5) | 233.0 (167.7) | 310.2(207.0) | 471.9 (303.3) |
| Sedentary time (min/week) | 3949.8 (763.8) | 4447.8 (732.1) | 4094.6 (633.9) | 3834.5 (622.0) | 3421.2 (668.1) |
Continuous variables are presented as mean (SD); categorical variables are presented as n (%).
aTownsend deprivation index = a composite area-level measure of deprivation based on unemployment, non-car ownership, non-home ownership, and household overcrowding; a higher score indicates higher deprivation.
bRegular NSAID use was assessed through a questionnaire. Participants were asked about their regular use (defined as most days of the week for the last 4 weeks) of common over-the-counter medications, including various brand names for aspirin, ibuprofen, paracetamol, and codeine. The questionnaire provided a comprehensive list of brand names to ensure accurate reporting of NSAID use, including combinations and less commonly recognized trade names.
BMI, Body Mass Index; NSAID, nonsteroidal anti-inflammatory drug; HRT, hormone replacement therapy; LPA, light physical activity; MVPA, moderate-to-vigorous physical activity.