Table 2.
Association of light, moderate-to-vigorous physical activity and sedentary time with the risk of incident ulcerative colitis.
| Exposure | Total | Events (ratea) | Crude Model | Adjusted Modelb |
|---|---|---|---|---|
| HR (95%CI), p-value | HR (95%CI), P-value | |||
| Light physical activity, min/week | ||||
| Q1 (<1634.9) | 23,675 | 66 (3.2) | Ref | Ref |
| Q2 (1634.9- to <2068.7) | 23,668 | 64 (3.1) | 0.97 (0.66, 1.43), 0.873 | 1.06 (0.72, 1.58), 0.758 |
| Q3 (2068.7- to <2552.1) | 23,677 | 48 (2.3) | 0.68 (0.44, 1.04), 0.0736 | 0.77 (0.49, 1.19), 0.241 |
| Q4 (>2552.1) | 23,656 | 65 (3.1) | 0.94 (0.64, 1.40), 0.774 | 1.10 (0.73, 1.66), 0.658 |
| P for trend | 0.437 | 0.986 | ||
| Moderate to vigorous physical activity, min/week | ||||
| Q1 (<112.5) | 23,743 | 81 (4.0) | Ref | Ref |
| Q2 (112.5- to <231.5) | 23,597 | 65 (3.2) | 0.75 (0.52, 1.08), 0.125 | 0.78 (0.53, 1.13), 0.188 |
| Q3 (231.5- to <402.3) | 23,689 | 46 (2.2) | 0.52 (0.34, 0.78), 0.00174 | 0.53 (0.35, 0.82), 0.00426 |
| Q4 (>402.3) | 23,647 | 51 (2.5) | 0.56 (0.37, 0.84), 0.00486 | 0.57 (0.37, 0.87), 0.00991 |
| P for trend | 0.0009 | 0.00262 | ||
| Sedentary time, min/week | ||||
| Q1 (<3437.9) | 23,673 | 58 (2.8) | Ref | Ref |
| Q2 (3437.9- to <3950.9) | 23,672 | 53 (2.6) | 1.00 (0.65, 1.54), 0.992 | 0.99 (0.64, 1.52), 0.964 |
| Q3 (3950.9- to <4457.8) | 23,668 | 66 (3.2) | 1.17 (0.78, 1.77), 0.448 | 1.13 (0.75, 1.72), 0.555 |
| Q4 (>4457.8) | 23,663 | 66 (3.2) | 1.26 (0.84, 1.89), 0.269 | 1.11 (0.73, 1.70), 0.621 |
| P for trend | 0.196 | 0.508 | ||
aIncidence rates per 10,000 person-years.
bAdjusted for age, sex, body mass index, Townsend Deprivation Index, educational level, smoking status, alcohol consumption, and pre-existing chronic conditions (hypertension, diabetes and cardiovascular disease), non-steroid anti-inflammatory drug use, antibiotics use, and, among female participants, use of oral contraception, menopausal status, hormone therapy and parity.
HR, hazard ratio; CI, confidence interval; Ref, reference.