Table 3.
Associations between physical activity pattern and incident ulcerative colitis across varying MVPA thresholda.
| Activity threshold | Activity Patternb | Event (ratec) | Hazard ratio (95% CI) | p_value |
|---|---|---|---|---|
| 25th percentile (≥112.5 min MVPA/week) | Inactive (n = 23,480) | 81 (4.01) | Ref | Ref |
| Weekend warrior (n = 45,559) | 111 (2.78) | 0.74 (0.55–0.99) | 0.046 | |
| Regular activity (n = 25,060) | 51 (2.32) | 0.59 (0.41–0.84) | 0.004 | |
| Guideline-based (≥150 min MVPA/week) | Inactive (n = 31,414) | 101 (3.73) | Ref | Ref |
| Weekend warrior (n = 38,772) | 93 (2.74) | 0.78 (0.58–1.04) | 0.091 | |
| Regular activity (n = 23,913) | 49 (2.34) | 0.63 (0.44–0.90) | 0.011 | |
| 50th percentile (≥231.5 min MVPA/week) | Inactive (n = 47,032) | 147 (3.61) | Ref | Ref |
| Weekend warrior (n = 26,235) | 58 (2.52) | 0.72 (0.53–0.99) | 0.043 | |
| Regular activity (n = 20,832) | 38 (2.08) | 0.57 (0.39–0.82) | 0.003 | |
| 75th percentile (≥402.0 min MVPA/week) | Inactive (n = 70,568) | 194 (3.16) | Ref | Ref |
| Weekend warrior (n = 11,044) | 25 (2.58) | 0.85 (0.55–1.30) | 0.449 | |
| Regular activity (n = 12,487) | 24 (2.18) | 0.69 (0.45–1.06) | 0.088 |
aAdjusted for age, sex, body mass index, townsend deprivation index, educational level, smoking status, alcohol consumption, and pre-existing chronic conditions (hypertension, diabetes and cardiovascular disease), non-steroid anti-inflammatory drug use, antibiotics use, and, among female participants, use of oral contraception, menopausal status, hormone therapy and parity.
bInactive defined as weekly MVPA below the specified threshold.
cIncidence rates per 10,000 person-years.
MVPA, moderate-to-vigorous physical activity; CI, confidence interval; Ref, reference.