Table 2.

Reported methodological quality of included randomised clinical trials assessing effects of hepatitis B vaccines and immunoglobulin for newborn infants of mothers positive for hepatitis B surface antigen

Trial	Generation of allocation sequence	Allocation concealment	Blinding	Methodological quality
Assateerawatt 199323	Adequate	Unclear	Not done	Low
Beasley 19837,24	Unclear	Unclear	Unclear	Low
Beasley 198325	Unclear	Unclear	Unclear	Low
Farmer 198726	Adequate	Unclear	Not done	Low
Garcia 199227	Unclear	Unclear	Unclear	Low
Grosheide 199329	Unclear	Adequate	Not done	Low
Halliday 199230	Adequate	Adequate	Adequate	High*
Hieu 200231	Adequate	Adequate	Not done	High*
Ip 198932,33,54	Unclear	Adequate	Adequate	High*
Kang 199534	Unclear	Unclear	Not done	Low
Khukhlovich 199635	Unclear	Unclear	Unclear	Low
Kuru 199536	Unclear	Unclear	Not reported	Low
Lee 199537-39	Unclear	Unclear	Not done	Low
Liu 198740	Unclear	Adequate	Adequate	High*
Lo 198528,41	Unclear	Unclear	Not done	Low
Lolekha 200242	Unclear	Unclear	Not done	Low
Oon 198643	Adequate	Unclear	Not done	Low
Piazza 198544	Adequate	Adequate	Unclear	High*
Pongpipat 198645	Unclear	Unclear	Not done	Low
Pongpipat 198846	Unclear	Unclear	Not done	Low
Pongpipat 198947	Unclear	Unclear	Not done	Low
Poovorawan 199748,49	Unclear	Unclear	Not done	Low
Sehgal 199250,51	Unclear	Unclear	Not done	Low
Theppisai 198752	Unclear	Unclear	Not done	Low
Theppisai 199053	Unclear	Unclear	Not done	Low
Xu 199555-57	Unclear	Unclear	Unclear	Low
Yeoh 198658	Unclear	Unclear	Not done	Low
Zhu 198760	Unclear	Unclear	Unclear	Low
Zhu 199459	Unclear	Unclear	Not done	Low

^*Trials having low risk of bias.