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. 2026 Sep 22;20:1849325. doi: 10.3389/fnhum.2026.1849325

Table 2.

Intervention measures and principles for cognitive impairment in elderly critically ill patients.

Category Early identification Early intervention
Main principles Correction of factors affecting cognitive function Hospital Elder Life Program (HELP)
eCASH care Multimodal analgesia: Behavioral Pain Scale (BPS), Critical-Care Pain Observation Tool (CPOT), Visual Analog Scale (VAS), Numerical Rating Scale (NRS)
Maintenance of light sedation: Richmond Agitation-Sedation Scale (RASS)
ICU interventions Medication safety management (benzodiazepines, opioids, anticholinergics, systemic corticosteroids), early mobilization, sleep improvement, reduction of physical restraints, and reorientation training
Specific Measures of Multicomponent Nonpharmacological Interventions Behavioral and psychological symptoms interventions Music therapy, touch therapy, aromatherapy
Home safety care Fall prevention, management of dangerous items, and ensuring environmental familiarity