Table 4.
Multivariate Cox Regression Analyses for Relapse-Free Survival.
| Variables | Relapse-free survival | |||
|---|---|---|---|---|
| HR (95% CI)* | AIC | p-Value | ||
| Preoperative GPS | 2238.8 | 0.59 | ||
| 0 | 1 | |||
| 1 | 1.00 (0.70-1.43) | |||
| 2 | 1.24 (0.80-1.92) | |||
| Preoperative NUn score (trichotomous) | 2231.2 | 0.011† | ||
| Low (≤5.60) | 1 | |||
| Intermediate (>5.60 to ≤7.12) | 1.00 (0.69-1.45) | |||
| High (>7.12) | 1.66 (1.09-2.53) | |||
| Preoperative NUn score (continuous) | 2232.1 | 0.015† | ||
| +1-unit | 1.14 (1.02-1.26) | |||
AIC: Akaike information criterion; ASA-PS: American Society of Anesthesiologists physical status; CI: confidence interval; GPS: Glasgow prognostic score; HR: hazard ratio; NUn: Noble and Underwood.
*Adjusted with age (≥70 years), gender, ASA-PS (3), tumor location, prior stoma creation, prior bridge-to-surgery intervention, emergency surgery, minimally invasive approach, adjuvant chemotherapy, tumor depth (T3-4), nodal status, lymphovascular involvement, and preoperative tumor marker positivity.
†p < 0.05.