FIG. 2.

The antiviral effects of P-PCIs and ACG, a conventional antiviral drug, are additive. Vero cells were infected with wild-type HSV-1 (wild type [WT]) or an ACG-resistant mutant (dlPstTK⁻). Infected cells were treated with the concentrations of ACG indicated on the x axes, in the presence of the concentrations of Rosco (top graphs) (□, 0 μM; ▪, 10 μM; ▵, 30 μM) or Purv (bottom graphs) (□, 0 μM; ▪, 60 μM; ▵, 15 μM). Viral titers at 20 h postinfection are plotted against concentrations of ACG.