. 2026 Oct 6. Online ahead of print. doi: 10.1039/d6ra07915f

Table 6. Selectivity indices of the E. elaterium extracts (SI = IC₅₀(HEK-293)/IC₅₀(cancer line)). Seed extracts and all aqueous-acetone/water extracts (IC₅₀ > 300 µg mL⁻¹) were not considered active and were excluded from the analysis.

Plant part	Solvent	HeLa	A549	HCT-116
Aerial parts	Ethyl acetate	0.97	0.75	1.31
Aerial parts	Acetone	0.89	0.65	0.88
Fruit peels	Ethyl acetate	1.00	1.02	1.08
Fruit peels	Acetone	0.86	0.72	0.99

Table 6. Selectivity indices of the E. elaterium extracts (SI = IC50(HEK-293)/IC50(cancer line)). Seed extracts and all aqueous-acetone/water extracts (IC50 > 300 µg mL−1) were not considered active and were excluded from the analysis.