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VB-85387 lowers NAS scores in LMCD-fed mice. NAS scoring was performed by a certified veterinary pathologist. A: Steatosis scores. B: Inflammation scores. C: Hepatocyte ballooning scores. D: NAS (n = 8). Statistical analysis was performed using two-way ANOVA followed by Tukey’s post hoc test. Data are presented as mean ± SD. ∗P ≤ 0.01; ∗∗P ≤ 0.001; ∗∗∗P ≤ 0.0001. NAS, NAFLD activity score; LMCD, low methionine, choline-deficient.
