Fig. 9.

VB-85387 normalizes adipocyte size and lipid storage. Epididymal tissue was sectioned and stained with H&E. The micrographs shown are representative images from adipose sections of n = 8 mice. A: Adipose morphology. B: Image J software was used to measure the width of individual adipocytes. The measurements were compiled and used to plot variations in adipocyte cell area caused by drug and diet treatments. C: AUC values. D: Adipose tissue free fatty acids. E: Adipose tissue triglycerides. F: Adipose tissue cholesterol. Statistical analysis: two-way ANOVA with Tukey's post hoc test. Data are mean ± SD. ∗P ≤ 0.01; ∗∗P ≤ 0.001; ∗∗∗P ≤ 0.0001; ∗∗∗P ≤ 0.0001. H&E, hematoxylin and eosin; AUC, area under the curve.