Table 2.
Serum and liver lipid levels in mice fed the LMCD
| Lipid | Chow | LMCD | LMCD + VB-85387 | LMCD + BMS-963272 |
|---|---|---|---|---|
| Liver cholesterol mg/g protein | 13.0 ± 2.8 | 12.2 ± 0.56 | 13.6 ± 1.7 | 15.4 ± 1.5 |
| Liver triglycerides mg/g protein | 108.1 ± 17.3 | 321.4 ± 22.6a | 220 ± 15.8c | 225.4 ± 20.4c |
| Serum cholesterol, mg/dL | 128.6 ± 11.3 | 51.37 ± 11.7a | 133.8 ± 10.8 | 140.6 ± 12.2 |
| Serum triglycerides, mg/dL | 141.6 ± 21.1 | 75.37 ± 14.2a | 119.3 ± 14.3b | 105.9 ± 10.7b |
| VLDL, mg/dL | 3.75 + 0.76 | 0.94 + 0.23a | 1.97 + 0.65c | 2.81 + 0.57c |
| LDL, mg/dL | 41.25 ± 10.8 | 35 ± 8.1 | 41.48 ± 5.7 | 30.12 ± 5.2 |
| HDL, md/dL | 97.5 + 13.6 | 15.2 + 3.1 | 95.7 + 15.9a | 107 + 15.8a |
n = 8.
Compared to mice fed the LMCD.
P ≤ 0.0001.
P ≤ 0.001.
P ≤ 0.01.