Table 2.

Cox models for per 1-point MetS score increase and incident CVD.

Model	N	Events	HR	95% CI	P
Model 1: Unadjusted	7889	815	1.234	1.176–1.294	<0.001
Model 2: Age + sex	7889	815	1.224	1.165–1.286	<0.001
Model 3: + Demographics	7889	815	1.220	1.161–1.282	<0.001
Model 4: + Biomarkers (no HDL-C)	7889	815	1.227	1.165–1.294	<0.001
Model 5: + CKM stage (primary)	7889	815	1.223	1.143–1.308	<0.001
Model 4-orig: + HDL-C	7889	815	1.265	1.185–1.351	<0.001
Model 5-orig: + HTN + DM	7889	815	1.164	1.074–1.262	<0.001

Model 5 (primary) adjusts for age, sex, marital status, education, smoking, drinking, BUN, creatinine, TC, LDL-C, CRP, uric acid, platelet count, and CKM stage. HDL-C, hypertension, and diabetes are excluded as MetS components. Original models (4-orig, 5-orig) shown for comparison.