Table 4.

Subgroup analysis of the association between MetS score and incident CVD.

Subgroup	N	Events	HR	95% CI	P value
Age <60 years	4433	416	1.249	1.135–1.375	<0.001
Age ≥60 years	3456	399	1.168	1.060–1.286	0.002
Male	3726	345	1.279	1.147–1.426	<0.001
Female	4163	470	1.165	1.066–1.273	<0.001
Never smoker	4796	513	1.196	1.098–1.302	<0.001
Former smoker	647	77	1.332	1.052–1.686	0.017
Current smoker	2446	225	1.229	1.078–1.401	0.002
CKM Stage 0	1620	105	1.410	0.950–2.091	0.088
CKM Stage 2	5143	558	1.196	1.107–1.291	<0.001
CKM Stage 3	891	120	1.162	0.969–1.392	0.105

HR, hazard ratio; CI, confidence interval. Per 1-point increase in MetS score, adjusted for age, sex, marital status, education, smoking, drinking, BUN, creatinine, TC, LDL-C, CRP, uric acid, and platelet count. CKM Stage 1 (n = 235) not shown due to model convergence limitations. P for interaction: age = 0.087, sex = 0.815, CKM stage = 0.188.