Table 13. EC₅₀ values and PI for active Ru(ii) complexes in different conditions against SK-MEL-28 melanoma cell line (400–700 nm, 75–92.5 minutes, 100 J cm⁻²).⁷⁹.

Complexes	Oxygen %	Cell viability assay (SK-MEL-28)
		EC50a ± SEMb (µM)				PIc
		Dark	400–700 nm	523 nm	633 nm	400–700 nm	523 nm	633 nm
56	18.5	50.7 ± n.dd	0.0294 ± 0.004	0.0771 ± 0.0046	12.5 ± 0.3	1724	658	4
	1	50.4 ± n.dd	0.320 ± 0.070	0.370 ± 0.035	50.6 ± n.dd	158	136	1
57	18.5	67.6 ± 0.8	(8.24 ± 3.38) × 10−5	(1.79 ± 0.18) × 10−3	1.80 ± 0.04	820 388	37 765	38
	1	69.5 ± 1.1	(2.09 ± 0.25) × 10−3	(7.20 ± 0.70) × 10−3	67.9 ± 1.9	33 254	9653	1

^aEC₅₀ = half-maximal effective concentration.

^bSEM = standard error of the mean.

^cPI represents the ratio between IC₅₀ values of complexes in dark and light conditions.

^dn.d. = not determined.