FIG. 3.

Effects of various extents of sequence identity on repeat deletion frequencies. (A) Repeat deletion rates for vectors with wild- type lacZ sequence in the 3′ repeat. The repeat vector structures are illustrated with boxed percentages (the 5′ and 3′ repeats are as indicated in the left and right boxes, respectively). For example, the second repeat vector structure listed represents pHIVlaac95%-WT, where the homology between repeats was 95%. Deletion rates were calculated as described in the text (means [bars] minus standard errors of the means [error bars] are shown). (B) Repeat deletion rates for vectors with wild-type lacZ sequence in the 5′ repeat. The methods for illustrating repeat vector structures and calculation of deletion rates are as described for panel A.