Table 1.
Distribution of sociodemographic and health-related characteristics by subjective cognitive complaints (≥ 2 versus < 2), xx city, 1989-2022
| Total (N = 4397) |
Subjective cognitive complaints |
p-valuea | ||
|---|---|---|---|---|
| SCCs < 2 (n = 2974) |
SCCs ≥ 2 (n = 1423) |
|||
| Demographic variables at baseline | ||||
| Age, mean (std), years | 46.16 (7.11) | 45.62 (6.84) | 47.29 (7.53) | <0.001b |
| Menopausal status, n (%) | <0.001 | |||
| Premenopausal | 3290 (74.82) | 2303 (77.44) | 987 (69.36) | |
| Postmenopausal | 1107 (25.18) | 671 (22.56) | 436 (30.64) | |
| Race/ethnicity1, n (%) | 0.104 | |||
| White | 3481 (82.45) | 2369 (83.30) | 1112 (80.70) | |
| African-American/ Latina | 673 (15.94) | 433 (15.23) | 240 (15.94) | |
| Asian/ Native American/ More than one race | 68 (1.61) | 42 (1.48) | 26 (1.89) | |
| Smoking2, n (%) | 0.003 | |||
| Never | 2051 (46.92) | 1431 (48.49) | 620 (43.66) | |
| Ever | 2320 (53.08) | 1520 (51.51) | 800 (56.34) | |
| Education3, n (%) | 0.007 | |||
| < College | 1723 (42.38) | 1117 (40.74) | 606 (45.77) | |
| College | 1070 (26.32) | 733 (26.73) | 337 (25.45) | |
| Graduate school or more | 1273 (31.31) | 892 (32.53) | 381 (28.78) | |
| Grams ethanol per week4, median (IQR), g | 42.92 (84.32) | 41.23 (83.46) | 46.49 (86.03) | 0.057b |
| BMI5c, n(%), kg/m2 | 0.029 | |||
| Underweight | 95 (2.17) | 73 (2.47) | 22 (1.55) | |
| Normal | 2884 (65.97) | 1970 (66.62) | 914 (64.59) | |
| Overweight | 979 (22.39) | 654 (22.12) | 325 (22.97) | |
| Obesity | 414 (9.47) | 260 (8.79) | 154 (10.88) | |
| DASH score6d, n (%) | 0.145 | |||
| Q1 (7-17) | 1094 (25.18) | 724 (24.62) | 370 (26.18) | |
| Q2 (18-20) | 944 (21.73) | 636 (21.63) | 308 (21.95) | |
| Q3 (21-24) | 1249 (28.75) | 877 (29.82) | 372 (26.51) | |
| Q4 (25-35) | 1057 (24.33) | 704 (23.94) | 353 (25.16) | |
| Follow-up variables at the time of SCD | ||||
| Age, mean (std), years | 78.74 (7.55) | 78.13 (7.24) | 80.02 (8.00) | <0.001b |
| History of cancer, n (%) | 1499 (34.09) | 987 (33.19) | 512 (35.98) | 0.068 |
| History of depression1, n (%) | 832 (18.99) | 441 (14.87) | 391 (27.61) | <0.001 |
| History of cardiometabolic diseasee, n (%) | 3013 (68.52) | 1977 (66.48) | 1036 (72.80) | <0.001 |
| Midlife physical activity, MET-hours per week | ||||
| Totalf, mean (std) | 45.12 (45.91) | 45.94 (45.21) | 43.42 (47.30) | 0.093b |
| Vigorous exercise, mean (std) | 18.75 (26.71) | 19.14 (26.02) | 17.94 (28.08) | 0.172b |
| Moderate exercise, mean (std) | 13.47 (18.41) | 13.97 (18.98) | 12.42 (17.12) | 0.007b |
| Mild exercise, mean (std) | 12.90 (14.18) | 12.82 (13.63) | 13.07 (15.28) | 0.610b |
| Subjective cognitive Complaints | ||||
| Number | ||||
| 0, n (%) | 1920 (43.67) | |||
| 1, n (%) | 1054 (23.97) | |||
| 2, n (%) | 666 (15.15) | |||
| 3, n (%) | 426 (9.69) | |||
| 4, n (%) | 152 (3.46) | |||
| 5, n (%) | 94 (2.14) | |||
| 6, n (%) | 85 (1.93) | |||
Missing = 175
Missing = 26
Missing = 331
Missing = 133
Missing = 25
Missing = 53
Pearson’s χ2 test unless otherwise indicated
t-Test for independent sample
Body Mass Index, estimates were calculated from self-reported weight and height. Underweight indicates BMI < 18.5, normal indicates 18.5 ≤ BMI < 25, overweight indicates 25 ≤ BMI < 30, and obesity indicates BMI ≥ 30.
Dietary Approaches to Stop Hypertension score, ranged from 7 to 35, with a higher score indicating a healthier diet. DASH score was divided into quartiles based on the following ranges: Q1, 7-17; Q2, 18-20; Q3, 21-24; and Q4, 25-35.
Cardiometabolic disease includes hypertension, diabetes, stroke, and coronary heart disease.
Total physical activity (MET-hours/week) includes vigorous MPA (9 MET), moderate MPA (4.5 MET), and mild MPA (3 MET).
Missing = 15