Table 2.
Associations between midlife physical activity (MET hours per week) and subjective cognitive complaints (≥ 2 versus < 2)
| Tertile of Midlife Physical Activity OR (95%CI) |
p-trend | OR (95%CI) per tertile | |||
|---|---|---|---|---|---|
| T1 | T2 | T3 | |||
| Total PA | |||||
| Median [range] | 6.0 [0-20.7] | 34.0 [20.9-51.1] | 79.0 [51.2-550.0] | ||
| Cases/Controls | 515/951 | 476/989 | 432/1034 | ||
| Model 1a | Ref | 0.94 (0.80-1.11) | 0.81 (0.69-0.95) | 0.008 | 0.90 (0.83-0.97) |
| Model 2b | Ref | 0.96 (0.81-1.11) | 0.80 (0.68-0.95) | 0.009 | 0.89 (0.82-0.97) |
| Vigorous PA | |||||
| Median [range] | 0 [0-0.2] | 9.6 [0.3-21.8] | 36.0 [22.0-377.5] | ||
| Cases/Controls | 506/959 | 472/989 | 445/1026 | ||
| Model 1 | Ref | 0.98 (0.83-1.15) | 0.88 (0.75-1.03) | 0.109 | 0.94 (0.87-1.02) |
| Model 2 | Ref | 1.01 (0.85-1.19) | 0.87 (0.74-1.02) | 0.111 | 0.93 (0.86-1.02) |
| Moderate PA | |||||
| Median [range] | 0 [0-0] | 9.0 [4.5-13.5] | 27.0 [18.0-324.0] | ||
| Cases/Controls | 620/1180 | 365/753 | 438/1041 | ||
| Model 1 | Ref | 1.01 (0.86-1.20) | 0.83 (0.71-0.97) | 0.020 | 0.91 (0.85-0.99) |
| Model 2 | Ref | 1.03 (0.87-1.22) | 0.84 (0.71-0.99) | 0.041 | 0.92 (0.85-1.00) |
| Mild PA | |||||
| Median [range] | 0 [0-3.0] | 9.0 [6.0-12.0] | 21.0 [15.0-150.0] | ||
| Cases/Controls | 427/876 | 432/924 | 564/1174 | ||
| Model 1 | Ref | 1.00 (0.85-1.19) | 1.02 (0.87-1.19) | 0.839 | 1.01 (0.93-1.09) |
| Model 2 | Ref | 1.00 (0.84-1.18) | 1.03 (0.88-1.21) | 0.683 | 1.02 (0.94-1.10) |
a
Model 1 was adjusted for age (continuous, baseline), menopausal status (premenopausal or postmenopausal), race (White, African-American, Latina, or other (Asian, Native American, more than one race)), education (< college, college, or ≥ graduate), smoking status (never or ever), Body Mass Index (underweight, normal, overweight, or obesity).
b
Model 2 had the same adjustments as model 1 plus alcohol consumption, history of cancer (yes or no), history of depression (yes or no), history of cardiometabolic disease (yes or no; including hypertension, diabetes, stroke, and heart disease), DASH score (7-17, 18-20, 21-24, or 25-35).