TABLE 2.
Effect of the probability of occurrence of deleterious mutations (p) on the process of fitness evolution through plaque-to-plaque transfers
| p | Slopea (T1-T50) | Meanb (Tc-T1,000) | Transfer no. at which stationary state starts (Tc) |
|---|---|---|---|
| 0.0025 | −0.0007 | ND | >1,000 |
| 0.005 | −0.002 | ND | >1,000 |
| 0.01 | −0.005 | 1.3 | ∼500 |
| 0.02 | −0.01 | 1.1 | ∼250 |
| 0.04 | −0.03 | 1.0 | ∼150 |
a
Slope of the regression line estimated when the logarithm of the fitness is represented as a function of the transfer number.
b
Mean is the value of the average fitness at the stationary state (fitness values from Tc to T1,000). The fitness values have been averaged over 200 independent trials. The parameter values used in the simulations are r = 5 and q = 0.001. ND, not determined.