FIG. 6.

Transduction of skeletal muscle. RRV or VSV-G/FIV vectors (30-μl portions) were bilaterally injected into the quadriceps of adult mice. Few β-galactosidase-expressing myocytes were detected in X-Gal-stained cross sections of the left quadriceps, 3 weeks after injection with either RRV (A)- or VSV-G (B)-pseudotyped FIV. (C) Quantification of β-galactosidase activity in the right quadriceps indicated that six of nine mice in the RRV group and three of four mice in the VSV-G group had β-galactosidase levels of >2-fold background (each bar represents an individual animal).