TABLE 6.

List of genes concomitantly modulated under basal and osteogenic conditions.

Category	Genes	Regulation pattern	Biological interpretation
Consistently downregulated	ZBTB11-AS1, FNDC1, RP11-73M18.10, KRT80, AHDC1, RP11-295K3.1, KCNH1, DNASE1, DGKD, FRA10AC1, MICAL3, PODN, COL11A1	↓ in OST and BAS	Reduced ECM remodeling, cytoskeletal organization, and signaling activity
Consistently upregulated	NT5E, PDCD10, PHLDA1, CCDC109B, PLA2G4A, LXN, RPGR, PTPN22, SLC16A6, TENM4	↑ in OST and BAS	Enhanced metabolic activity, immunomodulation, and cell survival pathways
Condition-dependent (opposite regulation)	ABCA7, SPTBN2	Opposite in OST vs. BAS	Context-dependent response (lipid transport, cytoskeleton remodeling)