Table 2.

IDERHA’s^a actions to enhance adherence to findable, accessible, interoperable, and reusable (FAIR) principles. The table maps concrete IDERHA design choices to the FAIR principles, organized by principle.

FAIR principle and aspect of FAIR			IDERHA’s actions
Findable
	Enforced standardized metadata	IDERHA recommends and uses metadata standards such as (Health)DCATb
	Searchability across repositories	IDERHA will provide data and algorithm catalogs with rich metadata for effective searches
	Unique identifiers and URIs for datasets, data services, and data providers	Datasets, data services, data providers within the IDERHA catalog will have unique IDs and URIs
Accessible
	Authentication/authorization mechanism	IDERHA uses authentication and authorization services and infrastructures such as eIDASc and AAId
	Data sensitivity	IDERHA architecture ensures that all data can be accessed only in compliance with GDPRe and other applying laws/guidelines
Interoperable
	Domain-specific focus	IDERHA defines data standards for data from domains not covered by OMOPf; a comprehensive data model for IDERHA is still under development
	Enforced standardized metadata	IDERHA recommends and uses metadata standards such as (Health)DCAT
	Consistency with local extensions	Currently ongoing work
Reusable
	Provenance and context	IDERHA’s metadata standard, (Health)DCAT, encompasses data versioning and source information. While HealthDCAT includes ETLg processes in text format, it currently lacks support for a machine-readable format
	License and usage information	IDERHA’s metadata standard (Health)DCAT covers license and usage information
	Dependence on licensed standards	Currently not addressed

^aIDERHA: Integration of Heterogeneous Data and Evidence Towards Regulatory and Health Technology Assessment Acceptance.

^bDCAT: Data Catalog Vocabulary.

^ceIDAS: Electronic Identification, Authentication, and Trust Services.

^dAAI: Authentication and Authorization Infrastructure.

^eGDPR: General Data Protection Regulation.

^fOMOP: Observational Medical Outcomes Partnership.

^gETL: extract, transform, and load.