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. Author manuscript; available in PMC: 2007 Jan 1.
Published in final edited form as: J Immunol. 2006 Jan 1;176(1):573–579. doi: 10.4049/jimmunol.176.1.573

FIGURE 7.

FIGURE 7.

Effect of PAFR inhibitor on LTA-induced phosphorylation of STAT1 and Jak2. A, RAW 264.7 cells were treated with (lane 1) none, (lanes 2, 4, and 6) PnLTA, or (lanes 3, 5 and 7) StLTA. Cells were treated with (lanes 4 and 5) a PAFR inhibitor or with (lanes 6 and 7) DMSO alone (0.01%). The PAFR inhibitor is CV6209 (1 μM) in DMSO (0.01%). Phosphorylated serine at position 727 is shown at the top, phosphorylated tyrosine at position 701 in the middle, and the “Total p38” at the bottom. B, RAW 264.7 cells were treated with (lanes 1) none, (lanes 2-4) StLTA (5 μg/ml), or (lanes 5-7) both StLTA (5 μg/ml) and CV6209 (1 μM) for the indicated time periods. Jak2 phosphorylation is shown at the top, and the “Total p38” is at the bottom.