TABLE 1.

Antibody response specific to EBO-Z in mice^a

Immunogen (immunization method)	Wk 1d		Wk 5
	ELISAb	PRNT50c	ELISAb	PRNT50c
L(EV) i.v.	1,000	<20	5,000	<20
L(EV) i.m.	1,000	<20	5,000	<20
EV i.v.	NDd	ND	500	<20
EV i.m.	ND	ND	500	<20
L i.v.	<100	<20	<100	<20
L i.m.	<100	<20	<100	<20

^aBALB/c mice were immunized i.v. or i.m. with L(EV), or EV or L and bled 1 and 5 weeks after the second immunization. Sera were pooled and analyzed for EBO-Z-specific and neutralizing antibodies (see Materials and Methods).

^bData shown represent the endpoint titers for ELISA.

^cPRNT₅₀ values represent reciprocal 50% endpoint dilutions for neutralizing antibodies.

^dND, not determined.