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. 2026 Sep 24;17:1883811. doi: 10.3389/fgene.2026.1883811

TABLE 2.

Comparison of thalassemia carrier rates among different ethnic groups, Guiyang, China, 2015 (N = 1,000).

Ethnic group Number of subjects (n) Number of carriers (n) P value (vs. Han)
Han 685 43 Reference
Buyi 75 13 <0.05
Dong 19 5 <0.01
Tujia 32 5 <0.05
Miao 77 6 >0.05

Overall chi-square test among the five ethnic groups: χ2 = 28.36, P < 0.05 (degrees of freedom = 4), indicating a statistically significant difference in carrier rates across groups. Pairwise comparisons were performed using the chi-square test with Bonferroni correction, using the Han group as the reference. Compared with Han, the Buyi, Dong, and Tujia groups showed significantly higher carrier rates (P < 0.05, <0.01, and <0.05, respectively), while the Miao group showed no significant difference (P > 0.05). All statistical analyses were conducted using SPSS 23.0.