Table 2.
Fahn-Tolosa-Marin tremor rating scale scores over time following frameless radiosurgical thalamotomy.
| Domain | Baseline | 3 months | p-value | 6 months | p-value | 9 months | p-value | 12 months | p-value |
|---|---|---|---|---|---|---|---|---|---|
| N=29 | N=26; N=25* | N=20; N=19* | N=17; N=16* | N=12; N=11* | |||||
|
| |||||||||
| Part A: Tremor Severity during rest, posture, action positions | 12 (9–14) | 9 (6–13) | 0·121 | 7 (5–8) | 0·001 | 10 (7–11) | 0·017 | 7 (5–11)* | 0·083 |
| Part B: Handwriting and Pouring | 18 (13–25) | 13 (7–17)* | 0·003 | 12 (7–15) | 0·001 | 14 (10–18) | 0·01 | 10 (5–18) | 0·005 |
| Part C: Functional Disability | 15 (13–17) | 10 (6–16) | 0·004 | 7 (6–10)* | 0·001 | 7 (6–11)* | 0·005 | 7 (6–11)* | 0·006 |
| Total | 46 (38–55) | 30 (21–45)* | 0·003 | 24 (19–31) | 0·001 | 32 (26–40) | 0·004 | 26 (14–39) | 0·003 |
Scores are summarized by median (interquartile range). Statistically significant p-values, obtained by Wilcoxon Signed Rank test comparing each post-treatment timepoint to the pre-treatment baseline, are bolded.