Table 1.
Characteristics of the study population (n = 903).
| Characteristics | Parameters | Case (%) |
|---|---|---|
| Age (years) | ||
| Median | 41 | |
| 25th-75th percentile | 35–50 | |
| Menopausal | ||
| Postmenopausal | 215 (23.8) | |
| Premenopausal | 688 (76.2) | |
| Number of pregnancies | ||
| <3 | 546 (60.5) | |
| ≥3 | 357 (39.5) | |
| Parity | ||
| ＜2 | 674 (74.6) | |
| ≥2 | 229 (25.4) | |
| Preoperative Cervical cytologya | ||
| NILM | 347 (38.4) | |
| ASCUS/AGC | 213 (23.6) | |
| LSIL | 148 (16.4) | |
| ASC-H | 87 (9.6) | |
| HSIL | 108 (12.0) | |
| Colposcopic impression of high-grade lesion | ||
| Yes | 838 (92.8) | |
| No | 65 (7.2) | |
| Colposcopic pathology (without ECC) | ||
| Chronic cervicitis | 12 (1.3) | |
| CIN1 | 130 (14.4) | |
| CIN2 | 395 (43.7) | |
| CIN3 | 366 (40.5) | |
| Cervical transformation zone (CTZ) | ||
| I | 369 (40.9) | |
| II | 246 (27.2) | |
| III | 288 (31.9) | |
| Endocervical involvement | ||
| Negative | 558 (61.8) | |
| Positive (CIN1) | 112 (12.4) | |
| Positive (CIN2-3) | 233 (25.8) | |
| Glandular involvement | ||
| Yes | 549 (60.8) | |
| No | 354 (39.2) | |
| Postoperative pathology | ||
| CIN2 | 464 (51.4) | |
| CIN3 | 435 (48.2) | |
| CIS | 4 (0.4) | |
| Surgical margin | ||
| Negative | 765 (84.7) | |
| Ectocervical margin | 43 (4.8) | |
| Endocervical margin | 77 (8.5) | |
| Basal margin | 18 (2.0) | |
| Postoperative HR-HPV persistence | ||
| 6 months | 210 (23.3) | |
| 12 months | 172 (19.0) | |
| 18 months | 158 (17.5) | |
| Residual or recurrent HSIL | ||
| Yes | 32 (3.5) | |
| No | 871 (96.5) | |
Values are presented as median (25th-75th percentile) for continuous variables (age) or n (%) for categorical variables. aPreoperative cervical cytology results (≤3 months before LEEP).
HR-HPV, high-risk human papillomavirus; NILM, no intraepithelial lesion or malignancy; ASC-US, atypical squamous cells of undetermined significance; AGC, atypical glandular cells; LSIL, low-grade squamous intraepithelial lesion; ASC-H, atypical squamous cells, cannot exclude HSIL; HSIL, high-grade squamous intraepithelial lesion; CIN, cervical intraepithelial neoplasia; CIS, carcinoma in situ.