TABLE 3.
Geometric mean diameters of papillomas on rabbits challenged with infectious CRPV DNAa
| Peptide | CRPV genome
|
CRPV L2− genomeb
|
||
|---|---|---|---|---|
| No. of papillomas/no. of challenge sites | GMD (cm3) | No. of papillomas/no. of challenge sites | GMD (cm3) | |
| CRPV L2.1 1 | 3/3 | 10.2 | 3/3 | 8.3 |
| CRPV L2.1 2 | 3/3 | 10.2 | NDc | ND |
| CRPV L2.2 1 | 2/3 | 7.3 | 2/3 | 6.0 |
| CRPV L2.2 2 | 3/3 | 5.1 | ND | ND |
| Control 1 | 3/3 | 18.1 | 3/3 | 17.3 |
| Control 2 | 3/3 | 16.5 | 3/3 | 20.6 |
a
Geometric mean diameters (GMD) are means for papillomas on three sites per treatment at 9 weeks postinfection.
b
CRPV L2− genome, genome rendered deficient for the expression of L2 via mutation in the start (ATG) codon.
c
ND, not determined.