Analysis of TREC levels during SIV infection in macaques. TREC levels within 100,000 CD4+ (A) and CD8+ (B) cells are depicted for 23 uninfected (+) and 15 SIV-infected (⋄) animals. At the time of sampling, the SIV-positive macaques had been infected for 6 to 8 months. Three different viral strains were examined, SIVmac239 (four animals), SIVmac251 (three animals), and SIVE660 (eight animals). SIV-positive TREC levels were highest in the youngest macaques and declined with age. No apparent isolate-specific differences in TREC levels were observed between the SIVmac239-, SIVmac251-, and SIVE660-infected macaques.