FIG. 1.

Sequence alignment for Gag polyproteins of HTLV/BLV retroviruses and description of HTLV-1 PPPY mutants. The PPPY motifs are shown in bold. (A) Sequence alignment for the MA-CA junction of HTLV-1, HTLV-2, and BLV. The HTLV-1 sequence is taken from the work of Seiki et al. (28), the HTLV-2 sequence from Shimotohno et al. (29), and the BLV sequence from Coulston et al. (3). The arrow indicates the putative cleavage site between MA and CA. (B) Description of the mutations introduced into the PPPY motif of HTLV-1.