Table 1. Baseline characteristics before and after IPTW.
| Before IPTW | After IPTW | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total (n = 306) | TACE (n = 187) | TARE (n = 119) | SMD | P | TACE (n = 187) | TARE (n = 119) | SMD | P | ||
| Sex | 306 | 187 | 119 | -0.043 | 0.714 | |||||
| Woman | 51 (16.7) | 30 (16.04) | 21 (17.65) | |||||||
| Man | 255 (83.3) | 157 (83.96) | 98 (82.35) | |||||||
| Age, yr | 306 | 187 | 119 | |||||||
| Mean ± SD | 68.3 ± 12.1 | 67.7 ± 13.0 | 69.1 ± 10.6 | 0.120 | 0.453 | |||||
| Median (min, max) | 69.9 (16.7, 91.7) | 69.8 (16.7, 91.7) | 70.0 (38.0, 89.0) | |||||||
| Tumor size | 306 | 187 | 119 | 0.178 | 0.133 | |||||
| >80 mm | 195 (63.7) | 113 (60.4) | 82 (68.9) | |||||||
| ≤80 mm | 111 (36.3) | 74 (39.6) | 37 (31.1) | |||||||
| Albumin | 306 | 187 | 119 | -0.368 | 0.002 | 0.014 | 0.911 | |||
| <4 g/dL | 165 (53.9) | 114 (61.0) | 51 (42.9) | 95.7 (53.5) | 62.4 (52.8) | |||||
| ≥4 g/dL | 141 (46.1) | 73 (39.0) | 68 (57.1) | 83.3 (46.5) | 55.8 (47.2) | |||||
| Bilirubin | 305 | 187 | 118 | -0.188 | 0.119 | |||||
| >1.2 mg/dL | 40 (13.1) | 29 (15.5) | 11 (9.3) | |||||||
| ≤1.2 mg/dL | 265 (86.9) | 158 (84.5) | 107 (90.7) | |||||||
| PT (INR) | 306 | 187 | 119 | -0.301 | 0.013 | 0.016 | 0.906 | |||
| >1.1 | 69 (22.6) | 51 (27.3) | 18 (15.1) | 41.7 (23.3) | 26.8 (22.6) | |||||
| ≤1.1 | 237 (77.5) | 136 (72.7) | 101 (84.9) | 137.3 (76.7) | 91.5 (77.4) | |||||
| PT, % | 306 | 187 | 119 | |||||||
| Mean ± SD | 95.9 ± 13.8 | 93.9 ± 13.9 | 99.0 ± 13.1 | 0.372 | 0.002 | 95.64 ± 13.61 | 95.99 ± 12.90 | 0.026 | 0.831 | |
| Median (min, max) | 96.0 (57.0, 143.0) | 95.0 (57.0, 130.0) | 97.0 (69.0, 143.0) | |||||||
| CP class | 306 | 187 | 119 | -0.146 | 0.220 | |||||
| A6, B7 | 65 (21.2) | 44 (23.5) | 21 (17.6) | |||||||
| A5 | 241 (78.8) | 143 (76.5) | 98 (82.4) | |||||||
| ALBI grade | 306 | 187 | 119 | -0.361 | 0.003 | 0.008 | 0.950 | |||
| 2 | 141 (46.1) | 99 (52.9) | 42 (35.3) | 82.0 (45.8) | 53.7 (45.4) | |||||
| 1 | 165 (53.9) | 88 (47.1) | 77 (64.7) | 96.9 (54.2) | 64.5 (54.6) | |||||
| AST | 306 | 187 | 119 | -0.332 | 0.005 | 0.005 | 0.965 | |||
| ≥40 IU/L | 177 (57.8) | 120 (64.2) | 57 (47.9) | 104.4 (58.3) | 68.7 (58.1) | |||||
| <40 IU/L | 129 (42.2) | 67 (35.8) | 62 (52.1) | 74.6 (41.7) | 49.6 (41.9) | |||||
| ALT | 306 | 187 | 119 | -0.284 | 0.017 | 0 | 1.000 | |||
| ≥40 IU/L | 126 (41.2) | 87 (46.5) | 39 (32.8) | 73.8 (41.2) | 48.7 (41.2) | |||||
| <40 IU/L | 180 (58.8) | 100 (53.5) | 80 (67.2) | 105.2 (58.8) | 69.5 (58.8) | |||||
| Creatinine | 306 | 187 | 119 | -0.206 | 0.089 | |||||
| ≥1.2 mg/dL | 38 (12.4) | 28 (15.0) | 10 (8.4) | |||||||
| <1.2 mg/dL | 268 (87.6) | 159 (85.0) | 109 (91.6) | |||||||
| AFP | 306 | 187 | 119 | 0.377 | 0.002 | 0.015 | 0.906 | |||
| ≥200 ng/mL | 110 (35.9) | 80 (42.8) | 30 (25.2) | 63.4 (35.4) | 41.0 (34.7) | |||||
| <200 ng/mL | 196 (64.1) | 107 (57.2) | 89 (74.8) | 115.5 (64.6) | 77.2 (65.3) | |||||
| PIVKA | 299 | 180 | 119 | -0.101 | 0.396 | |||||
| ≥200 mAU/mL | 239 (79.9) | 141 (78.3) | 98 (82.4) | |||||||
| <200 mAU/mL | 60 (20.1) | 39 (21.7) | 21 (17.7) | |||||||
| Platelet | 306 | 187 | 119 | -0.287 | 0.018 | 0.029 | 0.830 | |||
| <130 x103/µL | 53 (17.3) | 40 (21.4) | 13 (10.9) | 30.4 (17.0) | 18.8 (15.9) | |||||
| ≥130 x103/µL | 253 (82.7) | 147 (78.6) | 106 (89.1) | 148.5 (83.0) | 99.4 (84.1) | |||||
| HBV | 306 | 187 | 119 | -0.056 | 0.635 | |||||
| Negative | 98 (32.0) | 58 (31.0) | 40 (33.6) | |||||||
| Positive | 208 (68.0) | |||||||||
| HCV | 306 | 0.383 | ||||||||
| Negative | 292 (95.4) | |||||||||
| Positive | 14 (4.6) | |||||||||
| Alcohol | 306 | 0.579 | ||||||||
| Absent | 254 (83.0) | |||||||||
| Present | 52 (17.0) | |||||||||
Data are presented as number of patients (%) unless specified otherwise.
IPTW = inverse probability of treatment weighting, TACE = transarterial chemoembolization, TARE = transarterial radioembolization, SMD = standardized mean difference, SD = standard deviation, PT = prothrombin time, INR = international normalized ratio, CP = Child–Pugh, ALBI = albumin bilirubin, AST = aspartate aminotransferase, ALT = alanine aminotransferase, AFP = alpha-fetoprotein, PIVKA = protein induced by vitamin K absence, HBV = hepatitis B virus, HCV = hepatitis C virus