TABLE 3.

Frequency of CTL responses: relationship between HIV-1C proteins

Protein	P value (chi-square test) or difference in frequency (%)a:
	Gag p17	Gag p24	Gag p2/p7/p1/p6	Pol protease	Pol RT	Pol RNase H	Pol integrase	Vif	Vpr	Tat	Rev	Vpu	Env gp120	Env gp41	Nef
Gag p17		0.005	0.933	0.706	0.079	<0.001	0.005	0.862	0.121	0.204	0.841	0.118	<0.001	0.663	<0.001
Gag p24	−3.3		0.004	<0.001	<0.001	<0.001	<0.001	0.005	0.484	0.108	0.005	<0.001	<0.001	<0.001	0.560
Gag p2/p7/p1/p6	0.0	3.2		0.671	0.063	<0.001	0.004	0.888	0.121	0.206	0.863	0.105	<0.001	0.617	<0.001
Pol protease	0.5	3.8	0.6		0.275	<0.001	0.036	0.488	0.044	0.075	0.462	0.273	0.010	1.000	<0.001
Pol RT	1.4	4.7	1.5	0.9		<0.001	0.215	0.020	<0.001	<0.001	0.016	0.777	0.061	0.110	<0.001
Pol RNase H	3.6	6.8	3.6	3.0	2.1		0.006	<0.001	<0.001	<0.001	<0.001	0.009	0.012	<0.001	<0.001
Pol integrase	2.1	5.3	2.1	1.5	0.6	−1.5		<0.001	<0.001	<0.001	<0.001	0.764	0.663	0.004	<0.001
Vif	−0.3	3.0	−0.2	−0.8	−1.7	−3.8	−2.3		0.160	0.277	1.000	0.058	<0.001	0.399	<0.001
Vpr	−2.2	1.1	−2.1	−2.7	−3.6	−5.7	−4.2	−1.9		0.680	0.164	0.003	<0.001	0.017	0.245
Tat	−1.5	1.8	−1.5	−2.0	−2.9	−5.0	−3.5	−1.2	0.7		0.284	0.004	<0.001	0.024	0.026
Rev	−0.3	3.0	−0.3	−0.8	−1.7	−3.9	−2.4	0.0	1.9	1.2		0.052	<0.001	0.368	<0.001
Vpu	1.7	5.0	1.8	1.2	0.3	−1.8	−0.3	2.0	3.9	3.2	2.1		0.512	0.180	<0.001
Env gp120	2.3	5.5	2.3	1.7	0.8	−1.3	0.2	2.6	4.5	3.8	2.6	0.5		<0.001	<0.001
Env gp41	0.5	3.7	0.5	−0.1	−1.0	−3.1	−1.6	0.8	2.6	2.0	0.8	−1.3	−1.8		<0.001
Nef	−3.9	−0.6	−3.9	−4.4	−5.3	−7.5	−6.0	−3.6	−1.7	−2.4	−3.6	−5.7	−6.2	−4.4

^aThe P values from the chi-square test are shown in the upper triangle. According to the false discovery rate adjustment method (see Materials and Methods), only P values of <0.027 (in boldface) are significant. The differences in frequencies between the proteins are shown in the lower triangle.