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. 2026 Sep 28;17:1953711. doi: 10.3389/fimmu.2026.1953711

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Copyright © 2026 Montes De Oca Arena, Park, Choi and Morel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diagram illustrating PBX1’s regulatory roles in NK cells and macrophages, showing pathways for NK cell development, activity reduction by exosomal NEAT1, and macrophage fatty-acid uptake and IL-10 expression via PBX1-MEIS1-PREP1 complex. — Pbx1 mediated regulation of NK cells and macrophages.