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. 2026 Oct 5;373:fnag113. doi: 10.1093/femsle/fnag113

Figure 2.

Two panels. A, survival curves over 15 days: infected larvae survive like controls at first, then decline, while control survival stays high. B, photographs of larvae at days 0 and 15: infected larvae are smaller and misshapen.

Ehrlichia ruminantium induces delayed mortality in G. mellonella with characteristic macroscopic changes. (A) Kaplan–Meier survival curves comparing larvae (n = 10 per group) inoculated with 10⁵ E. ruminantium bacteria per larva versus PBS-injected controls. Data represent means of three independent replicates. Statistical significance was determined using the log-rank (Mantel–Cox) test (*P < 0.05). (B) Representative macroscopic changes in G. mellonella larvae at 0 and 15 days post-infection, showing reduced size and altered morphology in infected larvae compared to healthy controls. Scale bar, 5 mm.