Table 2.
Topic labels, top-weighted keywords, and proportions of the nine LDA-derived topics
| Topic | Top Keywords | Label | N | Proportion |
|---|---|---|---|---|
| 1 | wound_healing; wound_dressing; composite_hydrogel; antibacterial_activity; diabetic_wound; antibacterial_property; bacterial_infection; drug_release; injectable_hydrogel; chronic_wound | Wound Healing and Antibacterial Hydrogels | 387 | 0.07 |
| 2 | hydrogel_microspheres; delivery_system; drug_delivery; basic_fibroblast_growth_factor; oral_administration; therapeutic_effect; drug_release; hydrogel_microsphere; drug_delivery_system; magnetic_microspheres | Drug Delivery Systems and Bioactive Factor Release | 322 | 0.08 |
| 3 | drug_release; controlled_release; drug_delivery; drug_delivery_system; vitro_release; sustained_release; hydrogel_bead; drug_loaded; release_rate; release_profile | Controlled Drug Release | 950 | 0.23 |
| 4 | hydrogel_microspheres; sodium_alginate; hydrogel_bead; composite_hydrogel; adsorption_capacity; hydrogel_microsphere; cancer_cell; embolic_agent; methylene_blue; microfluidic_device | Alginate Composite and Embolic Microspheres | 475 | 0.09 |
| 5 | alginate_hydrogel; alginate_microspheres; drug_delivery; hydrogel_microparticles; biomedical_application; hydrogel_microspheres; tissue_engineering; silk_fibroin; alginate_bead; poly_ethylene_glycol | Alginate Microspheres for Biomedical Applications | 383 | 0.09 |
| 6 | tissue_engineering; stem_cell; tissue_regeneration; cell_viability; gelatin_microspheres; extracellular_matrix; cell_laden; growth_factor; cell_culture; cell_therapy | Tissue Engineering and Cell Delivery | 609 | 0.12 |
| 7 | plga_microspheres; sustained_release; drug_delivery_system; drug_delivery; chitosan_microspheres; poly_lactic_glycolic_acid; myocardial_infarction; long_term; blood_vessel; spinal_cord_injury | Long-Acting Polymeric Microspheres | 357 | 0.10 |
| 8 | bone_regeneration; hydrogel_microspheres; growth_factor; bone_defect; composite_scaffold; composite_hydrogel; bone_tissue_engineering; osteogenic_differentiation; sustained_release; bone_repair | Bone Regeneration and Osteogenic Repair | 570 | 0.10 |
| 9 | thermosensitive_hydrogel; drug_delivery; poly_isopropylacrylamide; composite_hydrogel; aqueous_solution; drug_carrier; chitosan_hydrogel; lower_critical_solution_temperature; phase_transition; sustained_release | Thermosensitive Hydrogel Delivery Systems | 346 | 0.12 |
Note: N indicates the number of records assigned to each topic based on the highest posterior topic probability. Proportion indicates the mean document-level topic probability across all included records. Therefore, N and proportion represent related but non-identical measures of topic prevalence