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Tissue distribution of IPC. (a) IPC can be identified within the extrafollicular T-cell-rich zones of LN by staining with anti-CD123 antibody (brown) (magnification, ×100). IPC can be visualized within the HEV. (b) IPC can also be identified in the parafollicular T-cell zone in tonsil (magnification, ×100). (c) Large numbers of IPC are seen in the cervical submucosa (magnification, ×100). (d) Rare IPC can also be found in the rectal submucosa (arrow) (magnification, ×100).
