TABLE 2.
Reactivity of SU-specific monoclonal antibodies with variant Env proteins
| Env variant | Degree of staininga with epitope-specific antibodies
|
|||
|---|---|---|---|---|
| Conformational
|
Linear (D) | |||
| F | G | H | ||
| WT | +++ | +++ | +++ | ++ |
| Y86C | +++ | +++ | +++ | ++ |
| F122S | +++ | +++ | +++ | + |
| G154K | +/− | +++ | +++ | ++ |
| D109N | + | +++ | ++ | + |
| F146L | + | ++ | + | + |
| D109G | +/− | ++ | + | + |
| N141K | +/− | ++ | + | ++ |
| R77G | − | + | + | ++ |
| G85D | − | + | + | ++ |
| C110R | − | + | + | +++ |
| P115S | − | +/− | + | ++ |
a
Percentages of fixed and permeabilized cells that stained for SU: −, none; +/−, <0.5%; +, 0.5 to 5%; ++, 5.1 to 10%; +++, >10%.