TABLE 1.
Nucleotide and amino acid changes between virus 31043 and Sabin strainsa
| Origin | Region | Nucleotide
|
Amino acid
|
||||
|---|---|---|---|---|---|---|---|
| Position | Sabin | 31043 | Position | Sabin | 31043 | ||
| Sabin 3 | 5′ NCR | 472 | U | C | |||
| 510 | C | U | |||||
| 610 | U | C | |||||
| 625 | U | C | |||||
| VP2 | 1037 | A | G | 30 | Asn | Asp | |
| VP3 | 1938 | G | A | 59 | Ser | Asn | |
| 2281 | U | C | |||||
| VP1 | 2479 | U | C | ||||
| 3170 | A | G | 232 | Thr | Ala | ||
| 3175 | U | C | |||||
| 3238 | C | U | |||||
| Sabin 2 | 2A | 3670 (3678) | U | C | |||
| 3676 (3684) | U | C | |||||
| 3A | 5119 (5127) | A | G | ||||
| 2C | 4120 (4128) | U | C | ||||
| 4342 (4350) | A | G | |||||
| Sabin 1 | 3D | 6194 (6203) | C | U | 73 | His | Tyr |
| 6211 (6220) | A | G | |||||
| 6725 (6734) | G | A | 249 | Glu | Lys | ||
a
The nucleotide position in the original Sabin strain is indicated in parentheses when different from 31043.