Skip to main content
. 2026 Sep 30;15(19):1785. doi: 10.3390/cells15191785
TACS TBX6-associated congenital scoliosis
PBMC Peripheral blood mononuclear cell
CT Computed tomography
iPSC induced pluripotent stem cell
CTRL maternal familial comparator
CS Congenital scoliosis
GSEA Gene Set Enrichment Analysis
SRS-22r Scoliosis Research Society-22 revised questionnaire
SSEA4 Stage-specific embryonic antigen-4
AP Alkaline phosphatase
IF Immunofluorescence
DAPI 4′,6-Diamidino-2-phenylindole
H&E Hematoxylin and eosin
PCR Polymerase Chain Reaction
qRT-PCR Quantitative reverse transcription polymerase chain reaction
RNA-seq RNA sequencing
PCA Principal component analysis
DEG Differentially expressed gene
GO Gene Ontology
KEGG Kyoto Encyclopedia of Genes and Genomes
ECM Extracellular matrix
TSS Transcription start site
O-GALNAc O-linked N-acetylgalactosamine
GalNAc N-Acetylgalactosamine
GAG Glycosaminoglycan
FGF Fibroblast growth factor
PI3K Phosphoinositide 3-kinase
AKT Protein kinase B
TGF-β Transforming growth factor beta
TNF Tumor necrosis factor
NF-κB Nuclear factor kappa B
mTORC1 Mechanistic target of rapamycin complex 1
ChIP Chromatin immunoprecipitation
CUT&Tag Chromatin immunoprecipitation followed by quantitative PCR
CUT&RUN Cleavage under targets and tagmentation
FDR False discovery rate
NES Normalized enrichment score
WB Western blot