| TACS | TBX6-associated congenital scoliosis |
| PBMC | Peripheral blood mononuclear cell |
| CT | Computed tomography |
| iPSC | induced pluripotent stem cell |
| CTRL | maternal familial comparator |
| CS | Congenital scoliosis |
| GSEA | Gene Set Enrichment Analysis |
| SRS-22r | Scoliosis Research Society-22 revised questionnaire |
| SSEA4 | Stage-specific embryonic antigen-4 |
| AP | Alkaline phosphatase |
| IF | Immunofluorescence |
| DAPI | 4′,6-Diamidino-2-phenylindole |
| H&E | Hematoxylin and eosin |
| PCR | Polymerase Chain Reaction |
| qRT-PCR | Quantitative reverse transcription polymerase chain reaction |
| RNA-seq | RNA sequencing |
| PCA | Principal component analysis |
| DEG | Differentially expressed gene |
| GO | Gene Ontology |
| KEGG | Kyoto Encyclopedia of Genes and Genomes |
| ECM | Extracellular matrix |
| TSS | Transcription start site |
| O-GALNAc | O-linked N-acetylgalactosamine |
| GalNAc | N-Acetylgalactosamine |
| GAG | Glycosaminoglycan |
| FGF | Fibroblast growth factor |
| PI3K | Phosphoinositide 3-kinase |
| AKT | Protein kinase B |
| TGF-β | Transforming growth factor beta |
| TNF | Tumor necrosis factor |
| NF-κB | Nuclear factor kappa B |
| mTORC1 | Mechanistic target of rapamycin complex 1 |
| ChIP | Chromatin immunoprecipitation |
| CUT&Tag | Chromatin immunoprecipitation followed by quantitative PCR |
| CUT&RUN | Cleavage under targets and tagmentation |
| FDR | False discovery rate |
| NES | Normalized enrichment score |
| WB | Western blot |