| 4-HNE | 4-hydroxynonenal |
| 6-OHDA | 6-hydroxydopamine |
| Aβ | amyloid-β |
| ACO1 | aconitase 1 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AD | Alzheimer’s disease |
| AIFM2 | apoptosis-inducing factor mitochondria-associated 2 |
| ALS | amyotrophic lateral sclerosis |
| AMPK | AMP-activated protein kinase |
| APP | amyloid precursor protein |
| ARE | antioxidant response element |
| BACE1 | beta-site amyloid precursor protein cleaving enzyme 1 |
| BDNF | brain-derived neurotrophic factor |
| BH4 | tetrahydrobiopterin |
| CAG | cytosine-adenine-guanine |
| CAT | catalase |
| CD98 | cluster of differentiation 98 |
| cGAS | cyclic GMP-AMP synthase |
| CISD1 | CDGSH iron–sulfur domain protein 1 |
| CNKI | China National Knowledge Infrastructure |
| CoQ10 | coenzyme Q10 |
| CR3 | complement receptor 3 |
| CTR1 | copper transporter 1 |
| DAT | dopamine transporter |
| DFO | deferoxamine |
| DHODH | dihydroorotate dehydrogenase |
| DJ-1 | protein/nucleic acid deglycase DJ-1 (PARK7) |
| DMT1 | divalent metal transporter 1 |
| EA | electroacupuncture |
| EAE | experimental autoimmune encephalomyelitis |
| EGCG | epigallocatechin gallate |
| ERK | extracellular signal-regulated kinase |
| FDX1 | ferredoxin 1 |
| FPN (FPN1) | ferroportin 1 |
| FSP1 | ferroptosis suppressor protein 1 |
| FTH (FTH1) | ferritin heavy chain 1 |
| FTL | ferritin light chain |
| FtMt | mitochondrial ferritin |
| GBD | Global Burden of Disease |
| GCH1 | GTP cyclohydrolase 1 |
| GCLC/GCLM | glutamate-cysteine ligase catalytic/modifier subunit |
| GCTR | gallic acid-tryptophan cyclodipeptide hybrid |
| GPX1 | glutathione peroxidase 1 |
| GPX4 | glutathione peroxidase 4 |
| GSH | glutathione |
| GSH-Px | glutathione peroxidase |
| GSK-3β | glycogen synthase kinase 3 beta |
| GSSG | oxidized glutathione |
| HD | Huntington’s disease |
| HIF-1α | hypoxia-inducible factor 1 alpha |
| HO-1 | heme oxygenase-1 |
| HTT | huntingtin |
| iASPP | inhibitor of apoptosis-stimulating protein of p53 |
| IC50 | half-maximal inhibitory concentration |
| ICS II | icariside II |
| ICV | intracerebroventricular |
| IKK | IκB kinase |
| IL-1β/IL-18 | interleukin-1 beta/interleukin-18 |
| IREB2 | iron-responsive element-binding protein 2 |
| IRP1/IRP2 | iron regulatory protein 1/2 |
| JC-1 | mitochondrial membrane potential-sensitive fluorescent probe |
| JNK | c-Jun N-terminal kinase |
| KD | dissociation constant |
| Keap1 | Kelch-like ECH-associated protein 1 |
| LC3B | microtubule-associated protein 1 light chain 3 beta |
| LIP | labile iron pool |
| lncRNA | long non-coding RNA |
| LOX | lipoxygenase |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LPS | lipopolysaccharide |
| MAPK | mitogen-activated protein kinase |
| MCAO | middle cerebral artery occlusion |
| MDA | malondialdehyde |
| MDM2 | murine double minute 2 |
| MMP | mitochondrial membrane potential |
| MPP+ | 1-methyl-4-phenylpyridinium |
| MPTP | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine |
| MRI | magnetic resonance imaging |
| MS | multiple sclerosis |
| mTOR | mechanistic target of rapamycin |
| NCOA4 | nuclear receptor coactivator 4 |
| NDs | neurodegenerative diseases |
| NeuN | neuronal nuclear protein |
| NF-κB | nuclear factor kappa B |
| NFTs | neurofibrillary tangles |
| NLRP1/NLRP3 | NOD-like receptor family pyrin domain-containing protein 1/3 |
| NOX | NADPH oxidase |
| NQO1 | NAD(P)H quinone oxidoreductase 1 |
| Nrf2 | nuclear factor erythroid 2-related factor 2 |
| OABL | 1,6-O,O-diacetylbritannilactone |
| OGD/R | oxygen–glucose deprivation/reoxygenation |
| p53 | tumor protein p53 |
| p62 | sequestosome 1 |
| PD | Parkinson’s disease |
| PEBP1 | phosphatidylethanolamine-binding protein 1 |
| PI3K | phosphoinositide 3-kinase |
| PINK1 | PTEN-induced kinase 1 |
| PL-OH | phospholipid alcohol |
| PL-OOH | phospholipid hydroperoxide |
| PSD95 | postsynaptic density protein 95 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 |
| PUFA | polyunsaturated fatty acid |
| PUFA-PL | polyunsaturated fatty acid-containing phospholipid |
| ROS | reactive oxygen species |
| RSL3 | RAS-selective lethal compound 3 (GPX4 inhibitor) |
| SAMP8 | senescence-accelerated mouse prone 8 |
| SIRT1/SIRT3 | sirtuin 1/sirtuin 3 |
| SLC3A2 | solute carrier family 3 member 2 |
| SLC7A11 (xCT) | solute carrier family 7 member 11 |
| SNHG1 | small nucleolar RNA host gene 1 |
| SNpc | substantia nigra pars compacta |
| SOD | superoxide dismutase |
| SPP1 | secreted phosphoprotein 1 |
| Sp1 | specificity protein 1 |
| Src | proto-oncogene tyrosine-protein kinase Src |
| STEAP3 | six-transmembrane epithelial antigen of prostate 3 |
| STING | stimulator of interferon genes |
| STZ | streptozotocin |
| T-AOC | total antioxidant capacity |
| TCM | traditional Chinese medicine |
| TCR | T-cell receptor |
| TDP-43 | TAR DNA-binding protein 43 |
| TF (Tf) | transferrin |
| TFA | total flavonoids of Astragalus |
| TFR1 (TFRC, TfR1) | transferrin receptor 1 |
| TH | tyrosine hydroxylase |
| TLR4 | toll-like receptor 4 |
| TNF-α | tumor necrosis factor alpha |
| TRAF6 | TNF receptor-associated factor 6 |
| TSG | 2,3,5,4′-tetrahydroxystilbene-2-O-beta-D-glucoside |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein 1 |
| VDAC | voltage-dependent anion channel |
| VDR | vitamin D receptor |
| WEM | water extract of Moschus |
| WHO | World Health Organization |
| YHG | icariin-astragaloside IV-puerarin mixture |
| α-syn | alpha-synuclein |