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. 2026 Oct 8;15(19):1790. doi: 10.3390/biology15191790
A2AR Adenosine A2A Receptor
A2BR Adenosine A2B Receptor
ACAT2 Acetyl-CoA Acetyltransferase 2
ACTH Adrenocorticotropic Hormone
AGEs Advanced Glycation End Products
AgRP Agouti-Related Peptide
AhR Aryl Hydrocarbon Receptor
AMPK AMP-Activated Protein Kinase
AMP Adenosine Monophosphate
AMT Amino Acid Metabolism and Transport*
APC Antigen-Presenting Cell
ARG1 Arginase-1
ARG2 Arginase-2
AVP Arginine Vasopressin
bHLH Basic Helix–Loop–Helix
BMAL1 Brain and Muscle ARNT-Like Protein 1
CAF Cancer-Associated Fibroblast
cAMP Cyclic Adenosine Monophosphate
CD8 Cluster of Differentiation 8
CD36 Cluster of Differentiation 36
CD39 Ectonucleoside Triphosphate Diphosphohydrolase-1 (ENTPD1)
CD73 Ecto-5′-Nucleotidase (NT5E)
CLOCK Circadian Locomotor Output Cycles Kaput
CNCDs Chronic Non-Communicable Diseases
COX-2 Cyclooxygenase-2
CRH Corticotropin-Releasing Hormone
CRY Cryptochrome
CTL Cytotoxic T Lymphocyte
DC Dendritic Cell
ECM Extracellular Matrix
ENK Enkephalin
ER Estrogen Receptor
ETC Electron Transport Chain
EV Extracellular Vesicle
EZH2 Enhancer of Zeste Homolog 2
FABP Fatty Acid-Binding Protein
FAO Fatty Acid Oxidation
FATP2 Fatty Acid Transport Protein 2 (SLC27A2)
FBP1 Fructose-1,6-Bisphosphatase 1
FFA Free Fatty Acid
GABA Gamma-Aminobutyric Acid
GAPDH Glyceraldehyde-3-Phosphate Dehydrogenase
GCN2 General Control Nonderepressible 2
G-CSF Granulocyte Colony-Stimulating Factor
GHT Geniculohypothalamic Tract
GH Growth Hormone
GH–IGF-1 axis Growth Hormone–Insulin-Like Growth Factor 1 Axis
GLUT1 Glucose Transporter 1
GM-CSF Granulocyte–Macrophage Colony-Stimulating Factor
GRP Gastrin-Releasing Peptide
Gs Stimulatory G Protein
H3K18la Histone H3 Lysine 18 Lactylation
H3K27me3 Trimethylation of Histone H3 Lysine 27
HCC Hepatocellular Carcinoma
HIF Hypoxia-Inducible Factor
HIF-1α Hypoxia-Inducible Factor 1 Alpha
HK Hexokinase
HK2 Hexokinase 2
HPA Hypothalamus–Pituitary–Adrenal Axis
IDO Indoleamine 2,3-Dioxygenase
IDO1 Indoleamine 2,3-Dioxygenase 1
IFN-I Type I Interferon
IFN-γ Interferon Gamma
IGF-1 Insulin-Like Growth Factor 1
IGL Intergeniculate Leaflet
IL-2 Interleukin-2
IL-10 Interleukin-10
IL-12 Interleukin-12
IS Immune System
JMJDs Jumonji Domain-Containing Histone Demethylases
Kla Lysine Lactylation
L-2-HG L-2-Hydroxyglutarate
LDH Lactate Dehydrogenase
LDHA Lactate Dehydrogenase A
LNCaP Lymph Node Carcinoma of the Prostate (human prostate cancer cell line)
M1 Classically Activated Macrophage
M2 Alternatively Activated Macrophage
MCT1 Monocarboxylate Transporter 1
MDSC Myeloid-Derived Suppressor Cell
miRNA MicroRNA
MOESIN Membrane-Organizing Extension Spike Protein
MR Magnetic Resonance
mTOR Mammalian Target of Rapamycin
NAD+ Nicotinamide Adenine Dinucleotide (oxidized form)
NADH Nicotinamide Adenine Dinucleotide (reduced form)
NAMPT Nicotinamide Phosphoribosyltransferase
NK Natural Killer Cell
NPAS2 Neuronal PAS Domain Protein 2
NPY Neuropeptide Y
NSCLC Non-Small-Cell Lung Cancer
OS Overall Survival
OXPHOS Oxidative Phosphorylation
PACAP Pituitary Adenylate Cyclase-Activating Polypeptide
PD-1 Programmed Cell Death Protein 1
PDAC Pancreatic Ductal Adenocarcinoma
PDH Pyruvate Dehydrogenase
PDK1 Pyruvate Dehydrogenase Kinase 1
PDK3 Pyruvate Dehydrogenase Kinase 3
PD-L1 Programmed Death-Ligand 1
PER Period Circadian Regulator Protein
PFS Progression-Free Survival
PHDs Prolyl Hydroxylases
PKA Protein Kinase A
PKM2 Pyruvate Kinase M2
PR Progesterone Receptor
PGE2 Prostaglandin E2
RHT Retinohypothalamic Tract
ROS Reactive Oxygen Species
SAM Sympatho–Adrenomedullary Axis
SCN Suprachiasmatic Nucleus
SOD2 Superoxide Dismutase 2
SREBP Sterol Regulatory Element-Binding Protein
STING Stimulator of Interferon Genes
T2DM Type 2 Diabetes Mellitus
TAM Tumor-Associated Macrophage
TAN Tumor-Associated Neutrophil
TCR T-Cell Receptor
TDO Tryptophan 2,3-Dioxygenase
TGF-β Transforming Growth Factor Beta
TIL Tumor-Infiltrating Lymphocyte
TLA Three-Letter Acronym
TLR8 Toll-Like Receptor 8
TME Tumor Microenvironment
TNBC Triple-Negative Breast Cancer
TNF Tumor Necrosis Factor
TNF-α Tumor Necrosis Factor Alpha (α)
TP53 Tumor Protein p53
Treg Regulatory T Cell
VEGF Vascular Endothelial Growth Factor
VEGFA Vascular Endothelial Growth Factor A
VIP Vasoactive Intestinal Peptide