AAV	adeno-associated virus
ABC	antibody biopolymer conjugate
ADAM	a disintegrin and metalloprotease
AGEs	advanced glycation end products
aMMP-8	active matrix metalloproteinase-8
ANG2	Angiopoietin 2
α-SMA	α-smooth muscle actin
BCVA	best-corrected visual acuity
BM	basement membrane
BMDMs	bone marrow-derived macrophages
BRB	blood–retina barrier
CCR2	C-C motif chemokine receptor 2
CECs	choroidal endothelial cells
CNV	choroidal neovascularization
COST	cone outer segment termination
CTGF	connective tissue growth factor
CX3CL1	C-X3-C motif chemokine ligand 1
CX3CR1	C-X3-C motif chemokine receptor 1
CXCL8	C-X-C motif chemokine ligand 8
DAF	decay-accelerating factor
DME	diabetic macular edema
DMI	diabetic macular ischemia
DR	diabetic retinopathy
DRIL	disorganization of the retinal inner layers
ECM	extracellular matrix
ELM	external limiting membrane
EMT	epithelial-to-mesenchymal transition
EndMT	endothelial-to-mesenchymal transition
ERM	epiretinal membrane
EZ	ellipsoid zone
FAK	focal adhesion kinase
FBN2	fibrillin-2
FDA	Food and Drug Administration
FH	factor H
FI	factor I
FSP-1	fibroblast-specific protein-1
FVM	fibrovascular membranes
GA	geographic atrophy
GAG	glycosaminoglycans
GALNS	galactosamine-6 sulfatase
GPCR	G protein-coupled receptor
HIF-1α	hypoxia-inducible factor-1α
IL-1β	interleukin-1β
LAP	latency-associated peptide
LATS	large tumor suppressor kinases
MAC	membrane attack complex
MCP	membrane cofactor protein
MCP-1	monocyte chemoattractant protein-1
MLCs	myosin light chains
MLCK	myosin light chain kinase
MMT	macrophage-to-myofibroblast transition
MNV	macular neovascularization
MST	mammalian STE20-like kinases
NAD+	nicotinamide adenine dinucleotide
nAMD	neovascular age-related macular degeneration
NF-κB	nuclear factor-κB
NICD	Notch intracellular domain
NLRP3	the NLR family pyrin domain-containing 3
NPDR	non-proliferative diabetic retinopathy
OCT	optical coherence tomography
OCTA	OCT-angiography
PBMCs	peripheral blood mononuclear cells
PDGF	platelet-derived growth factor
PDR	proliferative diabetic retinopathy
PDS	Port Delivery System
PMT	pericyte-to-myofibroblast transition
PPV	pars plana vitrectomy
RAGE	receptor for AGE
RGD	arginine–glycine–aspartate
ROCK	Rho-associated coiled-coil-containing protein kinase
ROS	reactive oxygen species
RPE	retinal pigment epithelium
S1P	sphingosine-1-phosphate
SHRM	subretinal hyperreflective material
SRF	subretinal fluid
T&E	treat-and-extend
TEAD	TEA domain family of DNA-binding proteins
TGF-β	transforming growth factor beta
TKI	tyrosine kinase inhibitor
TNF	tumor necrosis factor
TRD	tractional retinal detachment
VEGF-A	vascular endothelial growth factor A
ZEB	zinc finger E-box binding homeobox
ZO-1	Zonula Occludens-1