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. 2026 Oct 14;3(1):e20260040. doi: 10.70962/jhi.20260040

Figure 5.

A bar graph comparing IRT and antibiotic use over years of follow-up. Panel A: A bar graph showing the rate of immunoglobulin replacement therapy (IRT) use over years of follow-up. The horizontal axis represents years of follow-up categories (1 year, 2 years, 3 years, 4 years, 5 years) with the number of patients in each category. The vertical axis represents the IRT rate in total annual grams per N. Each category has bars for Year 1 to Year 5, with different colors representing each year. The number of patients (n) receiving IRT is labeled on each bar. Panel B: A bar graph showing the rate of antibiotic use over years of follow-up. The horizontal axis represents years of follow-up categories (1 year, 2 years, 3 years, 4 years, 5 years) with the number of patients in each category. The vertical axis represents the antibiotic rate in annual days of antibiotic use per N. Each category has bars for Year 1 to Year 5, with different colors representing each year. The number of patients (n) receiving antibiotics is labeled on each bar.

Annual IRT and antibiotic use during treatment with leniolisib. (A and B) Rate of (A) IRT or (B) antibiotic use by follow-up duration category within the OLE. N, number of patients in follow-up category; n, number of patients receiving IRT or antibiotic use.