Skip to main content
. 2026 Sep 24;27(19):8551. doi: 10.3390/ijms27198551
ACR/AAHKS American College of Rheumatology/American Association of Hip and Knee Surgeons
AMPA α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
ARTN Artemin
ATP Adenosine triphosphate
BDNF Brain-derived neurotrophic factor
CSI Central Sensitization Inventory
CX3CR1 C-X3-C motif chemokine receptor 1
DN4 Douleur Neuropathique en 4 Questions
eIF4E Eukaryotic translation initiation factor 4E
FcγRI Fc gamma receptor I
FPR1 Formyl peptide receptor 1
GDNF Glial cell line-derived neurotrophic factor
GFRα2 GDNF family receptor alpha 2
GFRα3 GDNF family receptor alpha 3
GFRα4 GDNF family receptor alpha 4
GRADE Grading of Recommendations Assessment, Development and Evaluation
HMGB1 High-mobility group box 1
IASP International Association for the Study of Pain
ICD-11 International Classification of Diseases, 11th Revision
IFN Interferon
IFN-α/β Interferon alpha/beta
IFNAR Interferon alpha/beta receptor
IL-17 Interleukin-17
IL-1β Interleukin-1 beta
IL-6 Interleukin-6
KCC2 Potassium-chloride cotransporter 2
KOOS Knee Injury and Osteoarthritis Outcome Score
LRP Low-density lipoprotein receptor-related protein
MAPK Mitogen-activated protein kinase
MNK1/MNK2 MAP kinase-interacting serine/threonine-protein kinases 1 and 2
MRI Magnetic resonance imaging
NaV1.8/1.9 Voltage-gated sodium channel subtypes NaV1.8 and NaV1.9
NF-κB Nuclear factor kappa B
NGF Nerve growth factor
NMDA N-methyl-D-aspartate receptor
NRTN Neurturin
p-eIF4E Phosphorylated eukaryotic translation initiation factor 4E
PBMC Peripheral blood mononuclear cell
PGE2 Prostaglandin E2
PROBAST + AI Prediction Model Risk of Bias Assessment Tool + Artificial Intelligence
PSPN Persephin
QST Quantitative sensory testing
RA Rheumatoid arthritis
RET Rearranged during transfection receptor tyrosine kinase
SANRA Scale for the Assessment of Narrative Review Articles
TAFA4 TAFA chemokine-like family member 4
TKA Total knee arthroplasty
TLR4 Toll-like receptor 4
TNF-α Tumour necrosis factor alpha
TRIPOD + AI Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis + Artificial Intelligence
TrkA Tropomyosin receptor kinase A
TrkB Tropomyosin receptor kinase B
TRPA1 Transient receptor potential ankyrin 1
TRPV1 Transient receptor potential vanilloid 1
US United States