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. 2026 Sep 30;27(19):8793. doi: 10.3390/ijms27198793
α-SMA Alpha-smooth muscle actin
AcSDKP N-acetyl-seryl-aspartyl-lysyl-proline
AGEs Advanced glycation end-products
AKT Protein kinase B
ALDOB Aldolase type B
AMPK AMP-activated protein kinase
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP1-AS2 ARAP1 antisense RNA 2
ATPIF1 ATP synthase inhibitory factor subunit 1
CD36 Cluster of differentiation 36
CKD Chronic kidney disease
COUP-TFII Chicken ovalbumin upstream promoter transcription factor II
DENV-2 Dengue virus serotype 2
DHAP Dihydroxyacetone phosphate
DKD Diabetic kidney disease
DHT Dihydrotestosterone
eGFR Estimated glomerular filtration rate
EMT Epithelial–mesenchymal transition
EndoMT Endothelial-to-mesenchymal transition
ERA Endothelin receptor antagonist
ESRD End-stage renal disease
EVs Extracellular vesicles
FBP Fructose-1,6-bisphosphate
FSP-1 Fibroblast-specific protein-1
GEC Glomerular endothelial cell
GPI Glucose-6-phosphate isomerase
GNPNAT1 Glucosamine-phosphate N-acetyltransferase 1
GPR87 G protein-coupled receptor 87
H3K14la Histone H3 lysine 14 lactylation
H3K18la Histone H3 lysine 18 lactylation
H4K12la Histone H4 lysine 12 lactylation
HADHA Hydroxyacyl-Coa dehydrogenase
HIF-1α Hypoxia-inducible factor 1-alpha
HK1 Hexokinase 1
HK2 Hexokinase 2
HMCs Human primary mesangial cells
IGFBP5 Insulin-like growth factor binding protein 5
IL-1β Interleukin-1 beta
IL-22 Interleukin-22
IREB2 Iron-responsive element-binding protein 2
KLF5 Krüppel-like factor 5
LDH Lactate dehydrogenase
LDHA Lactate dehydrogenase A
lncRNA Long non-coding RNA
MRA Mineralocorticoid receptor antagonists
mtROS Mitochondrial reactive oxygen species
NAD Nicotinamide adenine dinucleotide
NLRP3 NOD-, LRR- and pyrin domain-containing protein 3
OXPHOS Oxidative phosphorylation
PDK1 Pyruvate dehydrogenase kinase 1
PDK4 Pyruvate dehydrogenase kinase 4
PFK1 Phosphofructokinase 1
PFKP Phosphofructokinase platelet type
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
PGC-1α Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
PK Pyruvate kinase
PKM1 Pyruvate kinase M1
PKM2 Pyruvate kinase M2
PTM Post-translational modification
RAAS Renin–angiotensin–aldosterone system
RAGE Receptor for advanced glycation end-products
ROS Reactive oxygen species
RUNX1 Runt-related transcription factor 1
SAE1 SUMO-activating enzyme subunit 1
SGLT2 Sodium-glucose cotransporter 2
SIRPα Signal regulatory protein alpha
S1PR1 Sphingosine 1-phosphate receptor 1
SIRT3 Sirtuin 3
SIRT5 Sirtuin 5
SIRT6 Sirtuin 6
SLC2A1 Solute carrier family 2 member 1
Smad4 Mothers against decapentaplegic homolog 4
STZ Streptozotocin
SUMOylation Small ubiquitin-like modifier conjugation
TCM Traditional Chinese medicine
TECs Renal tubular epithelial cells
TERT Telomerase reverse transcriptase
TGF-β Transforming growth factor beta
TRIM65 Tripartite motif-containing protein 65
T1DM Type 1 diabetes mellitus
T2DM Type 2 diabetes mellitus
UBR5 Ubiquitin protein ligase E3 component N-recognin 5
VEGF Vascular endothelial growth factor
WTAP Wilms tumor 1-associating protein
YY1 Yin and Yang 1 transcription factor